Total synthesis of lespedezavirgatol |
| |
| Authors: | JinPing Qi HongZhu Deng DeRong Cao |
| |
| Institution: | 1. School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, China
2. School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China
|
| |
| Abstract: | Lespedezavirgatol, a novel 2-phenylbenzofuran compound which was isolated from Lespedeza virgata, was firstly synthesized from pyrogallic acid and 3,4-dimethoxyphenol as starting materials with 8 steps. The key steps for the total synthesis were the selective iodination at 3-position of 1,2-dimethoxy-4-methoxymethoxybenzene and the Sonogashira cross-coupling reaction between 4-iodo-2-methoxybenzene-1,3-diol and 2-ethynyl-3,4-dimethoxy-1-(methoxy-methoxy)-benzene. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
