| 几个新型呋喃氨基腈衍生物的合成及抗菌活性 |
| |
| 引用本文： | 李艳,吴鸣虎. 几个新型呋喃氨基腈衍生物的合成及抗菌活性[J]. 化学研究, 2011, 22(2): 44-46,51 |
| |
| 作者姓名： | 李艳 吴鸣虎 |
| |
| 作者单位： | 咸宁学院化学与生命科学系,湖北,咸宁,437100 |
| |
| 基金项目： | 湖北省科技厅重点项目(D20092806) |
| |
| 摘 要： | 用5-甲基-4-乙氧羰基呋喃氨基腈与芳醛反应制得Schiff碱,再采用NaBH4还原Schiff碱,得到3个新型5-甲基-4-乙氧羰基呋喃氨基腈衍生物.利用核磁共振谱(1H NMR)、红外光谱(IR),质谱(EI-MS)表征了产物的结构;并初步测定了产物的抗菌活性.结果表明,目标化合物的抗菌活性一般.
|
| 关 键 词： | 呋喃氨基腈衍生物 Sehiff碱 合成 抗菌活性 |
Synthesis of several 5-methyl-4-ethoxycarbonyl furan aminonitrile derivatives and their fungicidal activity |
| |
| LI Yan,WU Ming-hu. Synthesis of several 5-methyl-4-ethoxycarbonyl furan aminonitrile derivatives and their fungicidal activity[J]. Chemical Research, 2011, 22(2): 44-46,51 |
| |
| Authors: | LI Yan WU Ming-hu |
| |
| Affiliation: | LI Yan,WU Ming-hu(Department of Chemistry and Life Science,Xianning College,Xianning 437100,Hubei,China) |
| |
| Abstract: | Schiff bases were synthesized via reaction of 4-ethoxycarbonyl-5-methyl furan aminonitriles with aromatic aldehydes.Resultant Schiff bases were reduced with NaBH4 to provide 3 new 4-ethoxycarbonyl-5-methyl furan aminonitrile derivatives.The structures of the products were characterized by means of nuclear magnetic resonance spectroscopy(1H NMR),infrared spectrometry(IR) and electron-impact mass spectrometry(EI-MS).Besides,the antibacterial activity of the products was preliminarily evaluated.It was found th... |
| |
| Keywords: | furan aminonitrile derivative Schiff base synthesis antibacterial activity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
