Integrating sensitive quantification of hepatic metabolic functions by capillary electrophoresis with laser-induced fluorescence detection |
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Authors: | Toh Yi-Chin Zhang Jing Khong Yuet Mei Du Yanan Sun Wanxin Yu Hanry |
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Institution: | Institute of Biotechnology and Nanotechnology, A*STAR, The Nanos, #04-01, 31 Biopolis Way, Singapore 138669, Singapore. |
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Abstract: | We report the establishment of capillary electrophoresis with laser-induced fluorescence (CE-LIF) detection as a common analytical platform for sensitive quantification of both phase I and II metabolism in various hepatic in vitro models. |
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