Easy access to the family of thiazole N-oxides using HOF x CH3CN |
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Authors: | Amir Elizabeta Rozen Shlomo |
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Institution: | School of Chemistry, Tel-Aviv University, Tel-Aviv, Israel 69978. |
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Abstract: | An efficient procedure for transferring an oxygen atom to thiazole-containing compounds, resulting in the corresponding N-oxides, was developed by using HOF x CH3CN; mild reaction conditions, high yields and easy purification are the main features of this novel route, while X-ray structural analysis reveals a hydrogen bond between the N-oxide functionality and a water molecule. |
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