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One-pot Three-component Condensation Reactions in Water. An Efficient and Improved Procedure for the Synthesis of Furan Annulated Heterocycles
Authors:Ahmad Shaabani   Mohammad Bagher Teimouri  Hamid Reza Bijanzadeh
Affiliation:(1) Department of Chemistry, Shahid Beheshti University, Zip Code 1983963113, Tehran, Iran, IR;(2) Department of Chemistry, Tarbiat Modarres University, P.O. Box 14155-4838, Tehran, Iran, IR
Abstract:The environment-friendly one-pot three-component condensation reactions of 4-hydroxycoumarin or 4-hydroxy-6-methylpyrone, p-substituted benzaldehyde, and alkyl or aryl isocyanides to afford furocoumarines or furopyranones in water in good yields after about one hour at 75°C are reported.
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