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Protein Adsorption Switch Constructed by a Pillar[5]arene‐Based Host–Guest Interaction
Authors:Xuan Xiao  Guanrong Nie  Xiaoyan Zhang  Demei Tian  Prof Haibing Li
Institution:Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, P.R. China
Abstract:The interfacial properties of solid substrates are of importance for protein adsorption. Herein, we report a reversible protein adsorption switch based on the host–guest interaction of the butoxy pillar5]arene and adipic acid. By the detector of the contact angle (CA), atomic force microscopy (AFM), and luminoscope on the silicon substrate, the intelligent protein switch exhibits excellent adsorptivity for BSA and switch performance by pH regulation.
Keywords:bovine serum albumin  host–  guest systems  pH reversible switch  pillar[5]arene  proteins
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