Rhodium‐Catalyzed CS and CN Functionalization of Arenes: Combination of CH Activation and Hypervalent Iodine Chemistry |
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Authors: | Fen Wang Xinzhang Yu Zisong Qi Prof. Dr. Xingwei Li |
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Affiliation: | Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China) |
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Abstract: | Rhodium‐catalyzed sulfonylation, thioetherification, thiocyanation, and other heterofunctionalizations of arenes bearing a heterocyclic directing group have been realized. The reaction proceeds by initial RhIII‐catalyzed C?H hyperiodination of arene at room temperature followed by uncatalyzed nucleophilic functionalization. A diaryliodonium salt is isolated as an intermediate, which represents umpolung of the arene substrate, in contrast to previous studies that suggested umpolung of the coupling partner. |
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Keywords: | C H activation homogeneous catalysis hypervalent iodine rhodium umpolung |
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