Trifluoromethylselenolation of Aryldiazonium Salts: A Mild and Convenient Copper‐Catalyzed Procedure for the Introduction of the SeCF3 Group |
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| Authors: | Pavlo Nikolaienko Prof. Dr. Magnus Rueping |
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| Affiliation: | 1. Institute of Organic Chemistry, RWTH Aachen University, Aachen, Germany;2. King Abdullah University of Science and Technology (KAUST), Kaust Catalysis Center (KCC), Thuwal, Saudi Arabia |
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| Abstract: | The straightforward introduction of the trifluoromethylseleno group into aromatic and heteroaromatic compounds is accomplished by the utilization of readily available aryldiazonium tetrafluoroborates, potassium selenocyanate, and Ruppert–Prakash reagent. The reaction tolerates a wide range of aromatic and heteroaromatic diazonium salts and is also amenable to the synthesis of pentafluoroethyl selenoethers. Furthermore, the methodology can be applied directly starting from anilines. |
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| Keywords: | anilines copper diazonium salts fluorine organic chemistry |
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