The Reaction of 2-Aminoethyl- and 3-Aminopropyl-substituted Heterocycles with 2-Formyl-1,3-cyclanediones and 4-Oxo-3,1-benzoxazines |
| |
Authors: | A. Strakovs N. N. Tonkikh M. Petrova K. V. Ryzhanova E. Palitis |
| |
Affiliation: | (1) Riga Technical University, Riga, LV-1658, Latvia |
| |
Abstract: | The reaction of 2-formyl-1,3-cyclohexanedione, its 5,5-dimethyl, 5-phenyl and 5-(2-furyl) derivatives and of 2-formyl-1,3-indanedione and dehydroacetic acid with histamine, 3-(1-imidazolyl)propylamine, 3-(4-morpholyl)propylamine, 3-(2-pyrrolidon-1-yl)propylamine, 2-(1-piperazinyl)ethylamine, tryptamine, and 2-(aminomethyl)pyridine gave fifteen 2-aminomethylene derivatives. The reaction of these amines with 2-methyl-4-oxo-3,1-benzoxazine gave the 3-substituted 2-methyl-4(3H)-quinazolinones and with 4-oxo-2-phenyl-3,1-benzoxazine the monosubstituted N-benzoylanthranilic acid amides. |
| |
Keywords: | 2-aminoethyl- and 3-aminopropyl-substituted heterocycles 2-formyl-1,3-cyclanediones dehydroacetic acid 4-oxo-3,1-benzoxazines 2-aminomethylene-1,3-cyclanediones 3-substituted 4(3H)-quinazolinones monosubstituted N-benzoylanthranilic acid amides |
本文献已被 SpringerLink 等数据库收录! |
|