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Selective acid hydrolysis of 2-substituted-5-dimethylaminomethyleneaminopyrimidines to 5-amino- and 5-hydroxypyrimidines
Authors:T A Kizner  M A Mikhaleva  E S Serebryakova
Institution:(1) Novosibirsk Institute of Organic Chemistry, Siberian Section, Academy of Sciences of the USSR, 630090 Novosibirsk
Abstract:Conditions are described for the selective acid hydrolysis of 2-substituted-5-dimethylaminomethyleneaminopyrimidines in 0.2–2 M sulfuric acid, to give high yields of the corresponding 5-amino- and difficultly accessible 5-hydroxypyrimidines.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 801–803, June, 1990.
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