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An efficient synthesis of 1,5-benzodiazepine derivatives catalyzed by boric acid
Authors:Xin Zhou  Mei Yue Zhang  Shu Tao Gao  Jing Jun Ma  Chun Wang  Chao Liu Hebei Key Laboratory of Bioinorganic Chemistry  College of Sciences  Agricultural University of Hebei  Baoding   China
Affiliation:Hebei Key Laboratory of Bioinorganic Chemistry, College of Sciences, Agricultural University of Hebei, Baoding 071001, China
Abstract:1,5-Benzodiazepine derivatives have been synthesized by the condensation of o-phenylenediamines and ketones in the presence of boric acid as catalyst under mild conditions.This method is simple,environmentally benign and high yielding.
Keywords:1,5-Benzodiazepines  o-Phenylenediamines  Boric acid  Synthesis
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