Synthesis of Fluoro-, Monofluoromethyl-, Difluoromethyl-, and Trifluoromethyl-Substituted Three-Membered Rings |
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| Authors: | Jonathan Decaens Dr Samuel Couve-Bonnaire Prof Dr André B Charette Prof Dr Thomas Poisson Prof Dr Philippe Jubault |
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| Institution: | 1. INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), Normandie Univ, 76000 Rouen, France;2. Centre in Green Chemistry and Catalysis, Faculty of Arts and Sciences, Department of Chemistry, Université de Montréal, PO Box 6128, Station Downtown, Montréal, Québec, H3C 3J7 Canada;3. INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), Normandie Univ, 76000 Rouen, France
Institut Universitaire de France, 1 rue Descartes, 75231 Paris, France |
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| Abstract: | This Minireview describes recent advances toward the synthesis of fluoro-, monofluoromethyl-, difluoromethyl-, and trifluoromethyl-substituted three-membered rings such as cyclopropanes, aziridines, epoxides, episulfides, cyclopropenes, and 2 H-azirines. The main synthetic methodologies since 2016 for cyclopropanes and since 2010 for the other three-membered rings are reported. |
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| Keywords: | 3-membered rings difluoromethyl fluorine monofluoromethyl trifluoromethyl |
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