|
|||||
|
|
Self-Assembled Multivalent Ag-SR Coordination Polymers with Phosphatase-Like Activity |
|
| Authors: | Ying-Juan Cao Mei-Xia Yao Prof Leonard J Prins Rui-Xue Ji Ning Liu Prof Xiang-Ying Sun Prof Yun-Bao Jiang Prof Jiang-Shan Shen |
| Institution: | 1. Xiamen Key Laboratory of Optoelectronic Materials and Advanced Manufacturing, College of Materials Science and Engineering, Huaqiao University, Xiamen, 361021 China
These authors contributed equally to this work.;2. Department of Chemical Sciences, University of Padova, Via Marzolo 1, 35131 Padova, Italy;3. Xiamen Key Laboratory of Optoelectronic Materials and Advanced Manufacturing, College of Materials Science and Engineering, Huaqiao University, Xiamen, 361021 China;4. Department of Chemistry, College of Chemistry and Chemical Engineering, MOE Key Laboratory of Spectrochemical Analysis, Xiamen University, Xiamen, 361005 China |
| Abstract: | We show herein the phosphatase-like catalytic activity of coordination polymers obtained after adding Ag+-ions to thiols bearing hydrophobic alkyl chains terminated with a 1,4,7-triazacyclononane (TACN) group. The subsequent addition of Zn2+ -ions to the self-assembled polymers resulted in the formation of multivalent metal coordination polymers capable of catalysing the transphosphorylation of an RNA-model compound (2-hydroxypropyl-4-nitrophenyl phosphate, HPNPP) with high reactivity. Analysis of a series of metal ions showed that the highest catalytic activity was obtained when Ag+-ions were used as the first metal ions to construct the backbone of the coordination polymer through interaction with the -SH group followed by Zn2+-ions as the second metal ions complexed by the TACN-macrocycle. Furthermore, it was demonstrated that the catalytic activity could be modulated by changing the length of the hydrophobic alkyl chain. |
| Keywords: | Artificial phosphatases homogeneous catalysis Ag-SR coordination polymers self-assembly supramolecular chemistry |