Zr-MOF-808 as Catalyst for Amide Esterification |
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Authors: | Beatriz Villoria-del-Álamo Dr Sergio Rojas-Buzo Dr Pilar García-García Prof Dr Avelino Corma |
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Institution: | Instituto de Tecnología Química, UPV-CSIC, Universitat Politècnica de València-Consejo Superior de, Investigaciones Científicas, Avenida de los Naranjos s/n, 46022 Valencia, Spain |
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Abstract: | In this work, zirconium-based metal–organic framework Zr-MOF-808-P has been found to be an efficient and versatile catalyst for amide esterification. Comparing with previously reported homogeneous and heterogeneous catalysts, Zr-MOF-808-P can promote the reaction for a wide range of primary, secondary and tertiary amides with n-butanol as nucleophilic agent. Different alcohols have been employed in amide esterification with quantitative yields. Moreover, the catalyst acts as a heterogeneous catalyst and could be reused for at least five consecutive cycles. The amide esterification mechanism has been studied on the Zr-MOF-808 at molecular level by in situ FTIR spectroscopic technique and kinetic study. |
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Keywords: | amides heterogeneous catalysis kinetics metal–organic frameworks reaction mechanisms |
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