One-Pot Dual C−C Coupling Reaction via Site Selective Cascade Formation by PdII-Cryptate of an Amino-Ether Heteroditopic Macrobicycle |
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| Authors: | Sayan Sarkar Dr Piyali Sarkar Sandip Munshi Prof Pradyut Ghosh |
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| Institution: | School of Chemical Sciences, Indian Association for the Cultivation of Science (IACS), 2A and 2B Raja S.C. Mullick Road, Jadavpur, Kolkata, 700032 West Bengal, India |
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| Abstract: | Selectivity of aryl iodo over ethynyl iodo toward the Suzuki cross coupling reaction is explored by utilizing a palladium complex of amino-ether heteroditopic macrobicycle. Subsequently, unreacted ethynyl iodide undergoes homocoupling reaction in the same catalytic atmosphere, thereby representing a cascade dual C−C coupling reaction. Furthermore, this approach is extended for novel one-pot synthesis of unsymmetrical 1,3-diynes. |
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| Keywords: | 1 3-diyne C−C coupling macrobicycle regioselectivity supramolecular catalysis |
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