| Erythrocentaurin, Biosynthesis Postulation and Biomimetic Synthesis |
| |
| 作者姓名： | LEI Jun
YUAN Xiang-Hui
LIU Zhu-Lan
LIU Jian-Li |
| |
| 作者单位： | LEI,Jun（Department of Chinese Material Medica, Northwest University, Xi'an 710069）
YUAN,Xiang-Hui（Department of Chinese Material Medica, Northwest University, Xi'an 710069）
LIU,Zhu-Lan（Department of Chinese Material Medica, Northwest University, Xi'an 710069）
LIU,Jian-Li（Department of Chinese Material Medica, Northwest University, Xi'an 710069） |
| |
| 摘 要： | Erythrocentaurin is a relatively simple nature product isolated from the root of Gentiana macrophylla Pall.1] The co-existed of gentiopicroside from the same species led to speculation that erythrocentaurin is a biosynthesis product of gentiopicroside. The transformation of secologanin to carbocyclic aglycone under biomimetic condition has already known (Scheme 1).2,3] The postulated biosynthesis pathway of erythrocentaurin may be in the same way. In the process the cyclic hemiacetal of the aglycone opened to the dialdehyde which then undergoes a vinylogous aldol reaction, and then dehydroxylation and double bond migration to the title compound (Scheme 2).
|
Erythrocentaurin, Biosynthesis Postulation and Biomimetic Synthesis |
| |
| LEI,Jun,YUAN,Xiang-Hui,LIU,Zhu-Lan,LIU,Jian-Li.Erythrocentaurin, Biosynthesis Postulation and Biomimetic Synthesis[J].Chinese Journal of Organic Chemistry,2004,24(Z1):300-301. |
| |
| Authors: | LEI Jun YUAN Xiang-Hui LIU Zhu-Lan LIU Jian-Li |
| |
| Abstract: | Erythrocentaurin is a relatively simple nature product isolated from the root of Gentiana macrophylla Pall.1] The co-existed of gentiopicroside from the same species led to speculation that erythrocentaurin is a biosynthesis product of gentiopicroside. The transformation of secologanin to carbocyclic aglycone under biomimetic condition has already known (Scheme 1).2,3] The postulated biosynthesis pathway of erythrocentaurin may be in the same way. In the process the cyclic hemiacetal of the aglycone opened to the dialdehyde which then undergoes a vinylogous aldol reaction, and then dehydroxylation and double bond migration to the title compound (Scheme 2). |
| |
| Keywords: | |
| 本文献已被 万方数据 等数据库收录！ |
|
