Highly chemoselective reduction of carbonyl groups in the presence of aldehydes |
| |
| Authors: | Bastug Gulluzar Dierick Steve Lebreux Frédéric Markó István E |
| |
| Affiliation: | Université Catholique de Louvain, Laboratory of Organic and Medicinal Chemistry, Batiment Lavoisier, Place Louis Pasteur 1 bte L4.01.02., B-1348 Louvain-la-Neuve, Belgium. |
| |
| Abstract: | The exquisite ability of diethylaluminum benzenethiolate to efficiently discriminate between aldehydes and other carbonyl functions enables the chemoselective in situ reduction of ketones and methyl esters in the presence of aldehydes. This potent strategy avoids the usual drawbacks of traditional protecting group methodologies and could be extended to various other transformations. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
