A highly flexible green synthesis of 1H-pyrazolo[1,2-b]phthalazine- 5,10-dione derivatives with CuI nanoparticles as catalyst under solvent-free conditions |
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Authors: | Javad Safaei-Ghomi Hossein Shahbazi-Alavi Abolfazl Ziarati Raheleh Teymuri Mohammad Reza Saberi |
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Institution: | Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan 51167, Iran |
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Abstract: | CuI nanoparticles as an efficient catalyst have been used for the preparation of 1H-pyrazolo1,2-b]phthalazine-5,10-diones by the four-component condensation reaction of phthalic anhydride, hydrazine monohydrate, aromatic aldehydes and malononitrile or ethyl cyanoacetate under solventfree conditions in good to excellent yields, short reaction times and environmentally benign, milder reaction conditions. |
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Keywords: | NanoparticlesMulti-component reactionsSolvent-freePyrazolophthalazine |
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