新型螺环树状化合物的合成

利用环己二酮单腙芳构化反应, 得到9H, 9H, 11H, 11H, 12H, 12H-六氢化苯并[9,10]-(1H, 1H, 3H, 3H, 4H, 4H, 5H, 5H, 7H, 7H, 8H, 8H-十二氢)菲-2, 6, 10-三酮腙, 然后与季戊四醇反应, 得到9H, 9H, 11H, 11H, 12H, 12H-六氢化苯并[9,10]-(1H, 1H, 3H, 3H, 4H, 4H, 5H,5H, 7H, 7H, 8H, 8H-十二氢)菲-2,6,10-三酮缩三(2,2-二羟甲基-1,3-丙二醇), 再与9-[4-(2,6-二硫杂环己基)苯基]-3-[4-(二甲酯基甲基)苯基]-2,4,8,10-四氧杂螺[5.5]十一烷反应, 制成标题化合物. 中间体和标题化合物经过IR, 1H NMR, MS和元素分析表征.

Synthesis of Novel Spiro-dendrimer

A novel dendrimer-9H,9H,11H,11H,12H,12H-hexahydrobenzo[9,10]-1H,1H,3H,3H,4H,4H,5H,5H,7H,7H,8H,8H-dodecahydrophenanthrene-2,6,10-trione ketal-tri-(4-(4-(3-(9-(4-(2,6-disulfo-cyclohexyl)phenyl))-2,4,8,10-tetra-oxa-spiro[5.5]undecyl))phenyl-1,1-(2,6-dioxa)cyclohexanedimethanol was conveniently synthesized by the reaction of hexahydrobenzo[9,10] dodecahydrophenanthrene-2,6,10-trione ketal-tri-2,2-dihydromethyl-1,3-propanediol with 4-(4-(3-(9-(4-(2,6-disulfo-cyclohexyl)phenyl))-2,4,8,10-tetra-oxa-spiro[5.5]undecyl))phenyl-1,1-(2,6-dioxa)cyclohexanedimethanol.Some reaction intermediates were prepared with common chemical reagent.Novel dendrimer and intermediates were identified via IR,1H NMR and MS spectra and elemental analysis.