Copper-catalyzed azide-alkyne cycloaddition reaction in water using cyclodextrin as a phase transfer catalyst |
| |
Authors: | Shin Jung-Ah Lim Yeong-Gweon Lee Kyung-Hee |
| |
Institution: | 4-2, Agency for Defense Development, Yuseong, P.O. Box 35-4, 305-600 Daejeon, Republic of Korea. |
| |
Abstract: | 1,4-Disubstituted-1,2,3-triazoles were obtained in excellent yields from azides and terminal alkynes in H(2)O in the presence of catalytic amount of β-cyclodextrin as a phase transfer catalyst. Also, a one-pot CuAAC reaction was carried out successfully, affording 1,4-disubstituted-1,2,3-triazoles in good to high yields starting from an alkyl bromide, sodium azide, and terminal alkyne. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|