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Unlocking the Chain-Walking Process in Gold Catalysis** |
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| Authors: | Vivek W. Bhoyare Akash G. Tathe Prof. Vincent Gandon Dr. Nitin T. Patil |
| Affiliation: | 1. Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal Bypass Road, Bhauri, 462 066 Bhopal, India;2. Institut de Chimie Moléculaire et des Matériaux d'Orsay (UMR CNRS 8182), Paris-Saclay University, bâtiment Henri Moissan, 17 avenue des sciences, 91400 Orsay, France |
| Abstract: | The successful realization of gold-catalyzed chain-walking reactions, facilitated by ligand-enabled Au(I)/Au(III) redox catalysis, has been reported for the first time. This breakthrough has led to the development of gold-catalyzed annulation reaction of alkenes with iodoarenes by leveraging the interplay of chain-walking and π-activation reactivity mode. The reaction mechanism has been elucidated through comprehensive experimental and computational studies. |
| Keywords: | Annulation Chain-Walking Gold Catalysis Migratory Insertion β-Hydride Elimination |