Cargo Encapsulation in Photochromic Supramolecular Hydrogels Depends on Specific Guest-Gelator Supramolecular Interactions |
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| Authors: | Fabian Hoffmann Dr Anna-Lena Leistner Dr Susanne Kirchner Prof Dr Burkhard Luy Dr Claudia Muhle-Goll Dr Zbigniew Pianowski |
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| Institution: | 1. Institute for Biological Interfaces 4, Karlsruhe Institute of Technology KIT, P.O. Box 3640, 76021 Karlsruhe, Germany;2. Institute of Organic Chemistry, Karlsruhe Institute of Technology KIT, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany |
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| Abstract: | Photochromic supramolecular hydrogels are prospective materials for light-triggered drug release and bionanotechnology. Here we present a structural analysis of peptide-derived photochromic supramolecular hydrogels, which were physically loaded with a selection of biologically related compounds, using advanced techniques of nuclear magnetic resonance. The results enable detailed and correct understanding of the loading process and will allow for correct design of pharmacologically relevant systems for phototriggered drug delivery. |
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| Keywords: | azobenzene DOSY NOESY photochromic materials supramolecular hydrogels |
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