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Electrochemical Sensing of Paracetamol Using 3D Porous Laser Scribed Graphene Platform
Authors:Achraf Berni  Abdellatif Ait Lahcen  Aziz Amine
Institution:Laboratory of Process Engineering & Environment, Faculty of Sciences and Techniques, Hassan II University of Casablanca, P.A.146, Mohammedia, Morocco
Abstract:This work presents a novel disposable electrochemical sensor for paracetamol (PCM). The sensing platform is based on graphene, manufactured via laser-scribing technology (LSG) to produce a 3D-porous structure that offers a large surface area. The analytical performances of LSG electrodes were greatly enhanced due to the high catalytic activity of graphene produced by LSG technology compared to conventional carbon electrodes. Moreover, the results showed an outstanding adsorption feature towards PCM, allowing its detection at nanomolar level from 5 nM to 100 nM through pre-concentration. The proposed sensing strategy was successfully applied for the determination of PCM in human urine samples.
Keywords:Laser-scribed 3D-graphene  Flexible electrochemical sensors  Nanomolar detection  Paracetamol  Human urine  Environmental monitoring
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