RNA GG x UU motif binds K+ but not Mg2+ |
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| Authors: | Fan Yupeng Gaffney Barbara L Jones Roger A |
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| Institution: | Department of Chemistry and Chemical Biology, 610 Taylor Road, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA. |
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| Abstract: | A hairpin model of the group I intron P5b loop was synthesized with 8-13C-7-15N]-guanosine in the GG.UU metal binding site, 7-15N]-guanosine at a nonbinding site, and 3-15N]-uridine. 15N NMR showed specific binding for Co(NH3)63+ and K+, but not for Zn2+, Cd2+, or Mg2+. |
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