Synthesis of 5H-pyridazo[4,5-b]indoles by condensation of 2-acylindole-3-carboxylic acids with hydrazine |
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Authors: | G I Zhungietu L M Zorin V I Gorgos M A Rekhter |
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Institution: | (1) Institute of Chemistry, Academy of Sciences of the Moldavian SSR, 277028 Kishinev |
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Abstract: | 5H-Pyridazo4,5-b]indol-1-ones were obtained by heating 2-acetylindole-3- or 2-aroylindole-3-carboxylic acids with hydrazine hydrate in ethylene glycol or alcohol. 1-Chloro-5H-pyridazo4,5-b]indoles are formed by treatment of 5H-pyridazo4,5-b]indol-1-ones with phosphorus oxychloride.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1064–1066, August, 1982. |
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