Alternative two-step route to khellactone analogues using silica tungstic acid and sodium hydrogen phosphate |
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| Authors: | Bahador Karami Saeed Khodabakhshi Khalil Eskandari |
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| Institution: | 1411. Department of Chemistry, Yasouj University, 75918-74831, Yasouj, P.O. Box 353, Iran
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| Abstract: | A series of coumarins was synthesised via the silica tungstic acid-catalysed Pechmann reaction; some of these were employed for known three-component reactions with aromatic aldehydes and malononitrile in the presence of sodium hydrogen phosphate (Na2HPO4) as a basic catalyst, affording a variety of potentially anti-HIV active khellactone analogues. |
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