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The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids |
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| Authors: | Banerji Biswadip Conejo-Garcia Ana McNeill Luke A McDonough Michael A Buck Matthew R G Hewitson Kirsty S Oldham Neil J Schofield Christopher J |
| Affiliation: | Department of Chemistry and Oxford Centre for Molecular Sciences, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, UKOX1 3TA. |
| Abstract: | Cyclic beta-oxocarboxylic acids inhibit factor inhibiting hypoxia-inducible factor via ligation to the active site iron. |
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