Diastereomeric diterpenes from Coleus blumei. |
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| Authors: | C Y Ragas V F Templora J A Rideout |
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| Affiliation: | Chemistry Department, De La Salle University, Manila, Philippines. coscyr@mail.dlsu.edu.ph |
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| Abstract: | The chloroform extract of the air-dried leaves of Coleus blumei afforded a mixture of diastereomers of a new abietane type diterpene whose structures were elucidated by extensive one and two dimensional (ID, 2D) NMR and mass spectrometry. Acetylation of the mixture afforded a single compound. Antimicrobial tests on the diterpene indicate that it is active against Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans. |
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