纯水中有氧条件下Pd/C催化的无配体Suzuki反应简

报道一种在纯水中Pd/C催化的高效Suzuki反应体系，该体系无需除氧，且无外加配体和添加剂，底物普适性广泛，含有亲水或疏水基团的溴代芳烃都能被高效活化. 此外，对部分杂环芳烃与芳基硼酸的偶联反应也有较好的催化效果. 该催化剂可高效循环使用三次，且性能无明显下降.

Pd/C-catalyzed ligand-free and aerobic Suzuki reaction in water

A general and efficient catalytic system for Pd/C-catalyzed ligand-free aerobic Suzuki cross-coupling reactions was developed. The reaction tolerated a wide range of aryl bromides with a hydrophilic group or a hydrophobic group without any additives in water. Moreover, the catalytic system was successfully extended to the cross-couplings of heteroaryl halides with various arylboronic acids. The Pd/C catalyst could be reused three times without significant loss of catalytic activity.