Nanoparticle-based electrochemical detection in conventional and miniaturized systems and their bioanalytical applications: a review |
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Authors: | Siangproh Weena Dungchai Wijitar Rattanarat Poomrat Chailapakul Orawon |
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Institution: | aDepartment of Chemistry, Faculty of Science, Srinakharinwirot University, Sukumvit 23 Rd., Wattana, Bangkok 10110, Thailand;bDepartment of Chemistry, Faculty of Science, King Mongkut's University of Technology Thonburi, 91 Prachauthit Road, Bangmod Thung Kharu District, Bangkok 10140, Thailand;cDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok 10330, Thailand;dNational Center of Excellence for Petroleum, Petrochemicals and Advanced Materials, Chulalongkorn University, Patumwan, Bangkok 10330, Thailand |
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Abstract: | With recent advances in nanotechnology making more easily available the novel chemical and physical properties of metal nanoparticles (NPs), these have become extremely suitable for creating new sensing assays. Many kinds of NPs, including metal, metal-oxide, semiconductor and even composite-metal NPs, have been used for constructing electrochemical sensors. This article reviews the progress of NP-based electrochemical detection in recent applications, especially in bioanalysis, and summarizes the main functions of NPs in conventional and miniaturized systems. All references cited here generally show one or more of the following characteristics: a low detection limit, good signal amplification and simultaneous-detection capabilities. |
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Keywords: | Metal nanoparticles Electrochemical Sensors Miniaturized Systems Immunosensors Biosensors |
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