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A competent pot and atom-efficient synthesis of Betti bases over nanocrystalline MgO involving a modified Mannich type reaction
Authors:Bikash KarmakarJulie Banerji
Affiliation:a Gobardanga Hindu College, Department of Chemistry, Khantura, North 24 Parganas 743273, India
b Centre of Advanced Studies on Natural Products Including Organic Synthesis, Department of Chemistry, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India
Abstract:A simple, efficient, and eco-friendly method for the synthesis of 1-(α-aminoalkyl) naphthols, the Betti bases, has been carried out over a basic nanocrystalline MgO catalyst in aqueous condition. The method has been applied for the synthesis of a range of compounds with variable functionalities in excellent yield and selectivity.
Keywords:Multicomponent synthesis   Betti base   Nanocrystalline MgO   Heterogeneous   Water chemistry
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