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Aryloxy tetrazoles with axial chirality: Synthesis and partial resolution of 5‐(1‐(2‐methoxynaphthalen‐1‐yl)naphthalen‐2‐yloxy)‐1H‐tetrazole |
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| Authors: | Hossein A Dabbagh Alireza Najafi Chermahini Abbas Teimouri |
| Abstract: | 5‐(1‐(2‐Methoxynaphthalen‐1‐yl)naph‐ thalen‐2‐yloxy)‐1H‐tetrazole as the first aryloxy tetrazole with axial chirality was synthesized. Partial resolution was achieved using (S)‐proline and methylbenzylamine as the resolving agents. Best results were obtained using methylbenzylamine with 75–85% ee. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:416–419, 2006; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20241 |
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