Reactions of nitroxides with sulfur‐containing compounds,part IV: Synthesis of novel nitroxide (thio)ureas1

The reactions of 4‐isothiocyanato‐2,2,6,6‐tetramethylpiperidine‐1‐oxyl 2 and 4‐isocyanato‐2,2,6,6‐tetramethylpiperidine‐1‐oxyl 3 with selected amines and lower alcohols give the corresponding novel thioureas 4 , ureas 5 , thiocarbamates 6 , and carbamates 7 , all bearing the nitroxyl moiety. The characteristic features of EI mass spectra of (thio)ureas 4 and 5 are described. Some of the synthesized thioureas 4 , ureas 5 , thiocarbamates 6 , and carbamates 7 are moderately or weakly active against pathogenic fungi. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:393–401, 2006; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20228