A new eudesmane derivative and a new fatty acid ester from Sambucus williamsii |
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| Authors: | Yang Xujuan Wong Mansau Wang Naili Chan Albert Sun-Chi Yao Xinsheng |
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| Institution: | College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110015, China. |
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| Abstract: | 1,4,13-Trihydroxy-eudesm-11(12)-ene, a new eudesmane derivative (3), (9E)-8,11,12-trihydroxyoctadecenoic acid methyl ester, a new fatty acid ester (2) and tianshic acid (1) were obtained from the stems of Sambucus williamsii. Their structures were elucidated by physiochemical properties and spectroscopic analysis. Both compounds 1 and 2 showed stimulating effects on alkaline phosphatase activity of the osteoblastic UMR106 cell about 1.5 fold at 30 mumol/l while they had no effects on cell proliferation. |
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