维持性血液透析患者血清铁调素水平与心血管疾病的关系研究

目的观察分析维持性血液透析患者血清铁调素水平与心血管疾病的关系。方法选择惠州市第三人民医院2014年12月至2016年12月期间收治的维持性血液透析患者54例作为观察组,包含20例患者出现心血管疾病,另外选择接受体检的健康人25例作为对照组。结果观察组患者的血清铁调素水平、晚期氧化蛋白物及IL-6均显著高于对照组,比较差异具有统计学意义(P0.05);观察组发生心血管疾病患者血清铁调素水平显著高于非心血管疾病患者,数据比较差异具有统计学意义(P0.05)。结论血液透析患者血清铁调素水平与心血管疾病具有相关性,即可作为血透患者发生心血管疾病的新的独立危险因素,但需要进一步验证。

Relationship Between Serum Hepcidin Levels and Cardiovascular Disease in Maintenance Hemodialysis Patients

Objective To observe and analyze the relationship between maintaining hormone levels and cardiovascular disease serum hepcidin hemodialysis patients.Methods To maintain the random selection of my hospital from December 2014 to December 2016,the stable hemodialysis patients 54 cases as the observation group study,contains 20 cases of patients with cardiovascular disease,at the same time,healthy people accept a medical examination in our hospital 25 cases as control group.Results The patients in the observation group the serum hepcidin levels of advanced oxidation protein and IL-6 were significantly higher than in the control group,a statistically significant difference(P＜0.05);serum Hepcidin and ferritin,total iron binding capacity and IL-6 independent,patients in the observation group occurred in patients with cardiovascular disease serum hepcidin levels were significantly higher than that in patients with cardiovascular disease,with statistically significant data difference(P＜0.05).Conclusion Serum hepcidin levels in hemodialysis patients with cardiovascular disease can be associated with.The new independent risk factors in patients with cardiovascular disease as blood,but need further validation.