Mechanochemical-hydrothermal synthesis of calcium phosphate powders with coupled magnesium and carbonate substitution |
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Authors: | Wojciech L Suchanek Kullaiah Byrappa Pavel Shuk Richard E Riman Victor F Janas |
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Institution: | a Department of Ceramic and Materials Engineering, Rutgers University, 607 Taylor Rd, Piscataway, NJ 08854-8087, USAb Johnson & Johnson, Center for Biomaterials and Advanced Technologies, a Division of Ethicon, Rt. 22 W, P.O. Box 151, Somerville, NJ 08876-0151, USA |
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Abstract: | Magnesium- and carbonate-substituted calcium phosphate powders (Mg-, CO3-CaP) with various crystallinity levels were prepared at room temperature via a heterogeneous reaction between MgCO3/Ca(OH)2 powders and an (NH4)2HPO4 solution using the mechanochemical-hydrothermal route. X-ray diffraction, infrared spectroscopy, and thermogravimetric analysis were performed. It was determined that the powders containing both Mg2+ and CO32− ions were incorporated uniformly into an amorphous calcium phosphate phase while in contrast, the as-prepared powder free of these dopants was crystalline phase-pure, stoichiometric hydroxyapatite. Dynamic light scattering revealed that the average particle size of the room temperature Mg-, CO3-CaP powders was in the range of 482 nm-700 nm with a specific surface area between 53 and 91 m2/g. Scanning electron microscopy confirmed that the Mg-, CO3-CaP powders consisted of agglomerates of equiaxed, ≈20-35 nm crystals. |
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Keywords: | Calcium phosphate Hydroxyapatite Magnesium Nanoparticle Hydrothermal Synthesis Mechanochemical synthesis |
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