Chemistry of indole

Indolyl keto acids were synthesized by the action of dinitriles on substituted indoles under the conditions of the Hoesch reaction. The reaction of these keto acids with isatin in alkali leads to quinoline derivatives, whereas pyridazinones of the indole series are obtained with hydrazine hydrate.See 1] for communication XLIV.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1512–1517, November, 1975.