首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Inhibition of prefrontal protein synthesis following recall does not disrupt memory for trace fear conditioning
Authors:Sonja Blum  Jason D Runyan  Pramod K Dash
Institution:(1) The Vivian L. Smith Center for Neurologic Research and Department of Neurobiology and Anatomy, The University of Texas, Houston, Texas 77225, USA
Abstract:

Background  

The extent of similarity between consolidation and reconsolidation is not yet fully understood. One of the differences noted is that not every brain region involved in consolidation exhibits reconsolidation. In trace fear conditioning, the hippocampus and the medial prefrontal cortex (mPFC) are required for consolidation of long-term memory. We have previously demonstrated that trace fear memory is susceptible to infusion of the protein synthesis inhibitor anisomycin into the hippocampus following recall. In the present study, we examine whether protein synthesis inhibition in the mPFC following recall similarly results in the observation of reconsolidation of trace fear memory.
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号