A review on the effects of ionizing radiation on blood and blood components |
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| Affiliation: | 1. Dr Geoffrey P. Jacobs Associates, P.O. Box 16352, Jerusalem 91162, Israel;1. Department of Physics, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom;2. College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia;3. Department of Physics, King Abdulaziz University, Jeddah, Saudi Arabia;1. Division of Anesthesia and Intensive Care, Children''s Hospital V Buzzi, ASST FBF Sacco, Milan, Italy;2. Division of Cardiology, Children''s Hospital V Buzzi, ASST FBF Sacco, Milan, Italy;3. Department of Pediatrics, Children''s Hospital V Buzzi, ASST FBF Sacco, Milan, Italy;1. Mediterranean Institute for Life Sciences (MedILS), 21000 Split, Croatia;2. Inserm Unit 1001, Université Paris-Descartes, Sorbonne Paris Cité, Faculté de Médecine Paris Descartes, 75014 Paris, France;1. School of Health and Sports Sciences, University of the Sunshine Coast, Sunshine Coast, QLD 4558, Australia;2. School of Nursing, Midwifery, and Paramedicine, University of the Sunshine Coast, Sunshine Coast, QLD, Australia;3. Department of Emergency Medicine, Sunshine Coast Hospital and Health Service, Sunshine Coast, QLD, Australia |
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| Abstract: | The major application of blood irradiation is for the prevention of graft-versus-host disease on immunodeficient patients by the abrogation of T-lymphocytes. Despite screening of blood donations, transfusion associated transmission of infections due to contaminated blood products is common. Hence, there is potential for the application of irradiation for the inactivation of pathogenic microbes in blood products. Literature on the effect of radiation on blood components is reviewed in order to make a rational decision on the feasibility of their irradiation. |
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