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Intermolecular double quantum coherences (iDQc) and diffusion-weighted imaging (DWI) imaging of the human brain at 1.5 T
Authors:Fasano F  Capuani S  Hagberg G E  Branca T  Indovina I  Castriota-Scanderbeg A  Maraviglia B
Affiliation:

a Laboratory of Functional Neuroimaging, Fondazione Santa Lucia, IRCCS, 00179, Rome, Italy

b Enrico Fermi Center, Rome, Italy

c Istituto Nazionale Fisica della Materia (INFM) UdR Roma1 and Physics Department University “La Sapienza,” 00185, Rome, Italy

d Dep. Radiology, Fondazione Santa Lucia, IRCCS, 00179, Rome, Italy

Abstract:To study the sensitivity of intermolecular double quantum coherences (iDQc) imaging contrast to brain microstructure and brain anisotropy, we investigated the iDQC contrast between differently structured areas of the brain according to the strength and the direction of the applied correlation gradient. Thus diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) maps have been obtained. This procedure, which consists of analyzing both iDQc and DWI images at different gradient strength and gradient direction, could be a promising tool for clinical brain investigations performed with higher than 1.5 T magnetic fields.
Keywords:Intermolecular double quantum coherences (iDQc)   Diffusion weighted imaging (DWI)   Diffusion tensor imaging(DTI)   Contrasted-imaging
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