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Application of SiO2-Pr-SO3H as an efficient catalyst in the Ritter reaction
Authors:Ghodsi Mohammadi Ziarani  Alireza Badiei  Zeinab Dashtianeh  Parisa Gholamzadeh  Nina Hosseini Mohtasham
Affiliation:1. Department of Chemistry, Alzahra University, Vanak Square, Tehran, Iran
2. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
Abstract:Sulfonic-acid-functionalized silica was applied as an efficient heterogeneous acid catalyst in the Ritter reaction to prepare amides by reaction of various benzylic, allylic, and tertiary alcohols with various nitriles in good to excellent yields under solvent-free conditions. The simplicity of the reaction, recovery of catalyst without loss of reactivity, high yield of products, and short reaction time represent improvements over many existing methods.
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