A straightforward synthesis of ynones by reaction of dimethylalkynylaluminum reagents with acid chlorides |
| |
Authors: | Wang Baomin Bonin Martine Micouin Laurent |
| |
Institution: | Laboratoire de Chimie Thérapeutique, UMR 8638 associée au CNRS et à l'Université René Descartes, Faculté des Sciences Pharmaceutiques et Biologiques, 4 avenue de l'Observatoire, 75270 Paris Cedex 06, France. |
| |
Abstract: | Alkynyldimethylaluminum reagents react with various aromatic and aliphatic acid chlorides in a fast and efficient way. This reaction provides a simple entry to numerous ynones, using readily available, inexpensive, and nontoxic metalating agent, and does not require any transition metal as a catalyst. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|