Reactivity of methyl derivatives of nitrogenous heterocycles in vapor-phase catalytic oxidation

A study has been made of the reactivity of methylpyridines, methylpyrazines, and methylquinolines in oxidation in the vapor phase in the presence of -VO (PO₃)₂. Relationships have been found between the overall reaction rates of heterocyclic compounds and the charge on the ring nitrogen, and between the partial oxidation rate and the charge on the ring carbon atom adjacent to the methyl group. The partial oxidation rate of methylpyridines is given to a first approximation by the Hammet-type expression lnWa = –3.5 + 4.6 , with a correlation coefficient of 0.93.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 75–79, January, 1986.