| A Novel Hydroperoxyl Substituted Cembranolide Diterpene from Marine Soft Coral Lobophytum crassum |
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| 引用本文： | Shuai Wen YIN Yan Ping SHI Xiao Ming LI Bin Gui WANG. A Novel Hydroperoxyl Substituted Cembranolide Diterpene from Marine Soft Coral Lobophytum crassum[J]. 中国化学快报, 2005, 16(11): 1489-1491 |
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| 作者姓名： | Shuai Wen YIN Yan Ping SHI Xiao Ming LI Bin Gui WANG |
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| 作者单位： | [1]Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071 [2]Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 [3]Graduate School of the Chinese Academy of Sciences, Beijing 100039 |
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| 基金项目： | This work was financed in part by the innovation program of the Institute of 0ceanology, Chinese Academy of Sciences （I0CAS, L79032432） and the program of ＂Bairen Jihua＂ awarded from the Chinese Academy of Sciences （to B. G. Wang）. Y.P. Shi wishes thank the Key Laboratory of Experimental Marine Biology at I0CAS for partial financial support. |
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| 摘 要： | Marine soft corals, especially in the genera Sinularia, Sarcophyton, and Lobophytum, are rich source of novel cembranoid diterpenes1. Screening cembranoids in therapeutically relevant assay systems has shown that some of them possess HIV-inhibitory2, cytotoxic3, and anticancer activity4. In this paper, we report the structural elucidation of a new cembranolide isolated from the alcohol extract of marine soft coral Lobophytum crassum collected from South China Sea. Compound 1 was obtained a…
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| 关 键 词： | 珊瑚 药物 化学结构 抗癌性能 结构表征 中国 南海 化合物 |
| 收稿时间： | 2005-03-18 |
A Novel Hydroperoxyl Substituted Cembranolide Diterpene from Marine Soft Coral Lobophytum crassum |
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| Shuai;Wen;YIN;Yan;Ping;SHI;Xiao;Ming;LI;Bin;Gui;WANG. A Novel Hydroperoxyl Substituted Cembranolide Diterpene from Marine Soft Coral Lobophytum crassum[J]. Chinese Chemical Letters, 2005, 16(11): 1489-1491 |
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| Authors: | Shuai Wen YIN Yan Ping SHI Xiao Ming LI Bin Gui WANG |
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| Abstract: | A new cembranolide diterpene with a hydroperoxyl substitution was isolated from the marine soft coral Lobophytum crassum. The structure was elucidated on the basis of chemical and spectral methods. |
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| Keywords: | Lobophytum crassum 2-hydroperoxysarcophine cembranolide diterpene. |
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