KF负载氧化物高效催化缺电子烯与胺类的共轭加成反应

提供了一种新型高效的催化缺电子烯与胺类的共扼加成的反应体系。首先合成了一系列负载型氟化钾固体碱，并用于催化上述反应。通过对不同载体选择考察，筛选出氟化钾负载氧化镁固体碱为最佳催化剂。在进一步的催化反应过程中发现，该催化剂对反应具有很高的催化活性，能催化该反应在短短数分钟内完成。操作简单方便，不需要任何溶剂，催化剂价格低廉，反应收率高，可重复使用，具有化学选择性，适用范围广泛等均为该催化体系的主要特征。

Highly Efficient Conjugate Addition of Amines to Electron Deficient Alkenes Catalyzed by KF Supported on Metal Oxides

A novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes. A series of KF supported on different carriers have been synthesized for the conjugate addition amines to alkenes. After optimizing the reaction conditions, KF/MgO was chosen as the most efficient catalyst for the reactions. The results showed that the catalyst was very efficient for the conjugate addition of amines to electron deficient alkenes with excellent yields in several minutes. Operational simplicity, no need of any solvent, low cost of the catalyst used, high yields, reusability, excellent chemoselectivity and wide applicability are the key features of this methodology.