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New homochiral binaphthol-modified organolanthanide reagents for the enantioselective addition to aldehydes
Authors:Kelly Chibale   Nicholas Greeves   Lisa Lyford  J. Elizabeth Pease
Affiliation:

Robert Robinson Laboratories, Department of Chemistry, University of Liverpool, P.O. Box 147, Liverpool, L69 3BX, UK.

Abstract:Optically active secondary alcohols were obtained in high chemical yield and optical purity (up to 85% ee) from the lanthanide-mediated enantioselective addition of alkyl nucleophiles to aromatic aldehydes.
Keywords:
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