Asymmetric base pairing in the complex 5-fluorocytosinium chloride/5-fluorocytosine monohydrate |
| |
| Authors: | Gustavo Portalone Marcello Colapietro |
| |
| Institution: | (1) Department of Chemistry, University of Rome I ‘La Sapienza’, P.le Aldo Moro, 5, I-00185 Rome, Italy |
| |
| Abstract: | The structure of the complex 5-Fluorocytosinium chloride/5-Fluorocytosine monohydrate has been studied by X-ray diffraction
methods. It crystallizes in the monoclinic system, space group P 21
/n, a = 7.1257 (15), b = 8.351 (3), c = 21.520 (4) ?, β = 92.89 (8)°, V = 1279.0 (6) ?3, Z = 4. The structure consists of triple hydrogen-bonded 5-Fluorocytosine pairs, water molecules and chloride anions. Asymmetric
reversed Watson-Crick base pairing occurs between one protonated (5FcytH+) and one neutral 5-Fluorocytosine (5Fcyt) molecule. |
| |
| Keywords: | 5-Fluorocytosine 5-Fluorocytosinium chloride nucleobases crystal engineering molecular recognition |
| 本文献已被 SpringerLink 等数据库收录！ |
|
