Preparation and application of a thiamine-selective electrode |
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| Authors: | Chang-Yi Wang Yong-Li Guo |
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| Affiliation: | 1. Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran;2. Department of Chemistry, Islamic Azad University, Izeh, Iran;3. Department of Chemistry, Gobardanga Hindu College, India;4. Department of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran;1. Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India;2. Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India;3. Department of General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India |
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| Abstract: | A thiamine-selective graphite electrode with thiamine tetraphenylborate as the active material in poly(vinyl chloride) and dibutyl phthalate as the plasticizer at pH 2–5 provides a rapid, nearly Nernstian response to thiamine (as a bivalent cation) in the range 10−1 to 10−5 M. A rapid and accurate potentiometric determination of the thiamine monohydrochloride content of injection and tablet dosage forms is reported with quantitation by the known-addition, dilution method. |
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