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Correlation between chemical and physical surface properties and blood compatibility of PPE/EVA-blends
Authors:Doris Kleem  Birgit Severich  Hartwig Hcker
Abstract:The chemical and physical surface properties of a biomaterial are of high importance for the blood compatibility of an implant. Blends of poly(propylene-co-ethylene) with various amounts of poly(ethylene-co-vinyl acetate) (PPE/EVA-blends) were examined because of the varying surface hydrophilicity. Surface characterizations were performed by means of X-ray Photoelectron Spectroscopy (XPS), Infrared Spectroscopy in Attenuated Totalreflexion Mode (IR-ATR) in relation to dynamic contact angle and zeta potential measurements. The examination of the blood compatibility of the polymer surfaces was carried out in vitro in a modified BOWRY blood chamber with native whole human blood. A balanced ratio of polar and dispersive surface free energy and a zeta potential of −4 mV are the conditions for a good blood compatibility of the investigated PPE/EVA-blends.
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