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Characterization and use of a gamma radiation TLC scanner for radiochemical purity measurements of radiopharmaceutical kit preparations of99mTc(dmpe)2Cl 2 +
Authors:A P Carpenter Jr  T J Mysliwy  S I Sivakoff  M N Doshi  E M Wolshin  M A Matthew  G H Schnaper  V Subramanyam  L L Camin
Institution:(1) New England Nuclear, Radiopharmaceuticals Research Department, 331 Treble Cove Road, 01862 N. Billerica, Mass., (USA)
Abstract:A simple, low cost TLC scanner system for the characterization of gamma-emitting radiopharmaceuticals is described. The TLC gamma scanner has a linear response range of sim0.074 Mbq up to ge2.94 Mbq. The accuracy and reproducibility of measurement is better than ±5% (relative). The utility of this TLC scanner system is demonstrated by application to the radioanalytical evaluation of99mTc(dmpe)2Cl 2 + preparations. A comparison with HPLC radioanalytical separations is made.
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